Slay the Spire 2: The Regent Relic Tier List — Meta Picks (Apr 24)

👑 The Regent Relic Tier List

Top 15 Meta Picks & Reddit Community Watch (April 24, 2026)

#1
S+

Divine Destiny Relic

At the start of each combat, gain [star:6]. Regent
Versatility: ★5.0 Synergy: ★5.0 Act 1: ★5.0 Act 2: ★5.0 Act 3: ★4.5
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"Divine Destiny is basically free wins in Act 1. You just *do* things! It feels incredible to play with that much gas from the start. What a relic."
▲ 1200 upvotes
💡 Analysis: A foundational relic that provides an immense turn-one resource injection, fundamentally altering combat pacing and enabling immediate powerful plays. It accelerates scaling and provides crucial early game stability, making it a cornerstone for any Regent run.
#2
S+

Mini Regent Relic

The first time you spend [star:1] each turn, gain 1 Strength. Regent Regent
Versatility: ★4.5 Synergy: ★5.0 Act 1: ★4.0 Act 2: ★4.5 Act 3: ★4.5
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"Mini Regent is just free damage. Pop a 1-[star] card and boom, another Strength. Stacks so fast, makes your attacks absolutely shred!"
▲ 1300 upvotes
💡 Analysis: An exceptional damage-scaling relic that offers a reliable Strength boost every single turn with minimal [star] investment. It quickly turns The Regent into a formidable offensive threat, allowing attacks to rapidly outpace enemy defenses across all acts.
#3
S

Galactic Dust Relic

For every 10 [star:1] spent, gain 10 Block. Regent Regent
Versatility: ★4.0 Synergy: ★5.0 Act 1: ★3.5 Act 2: ★4.5 Act 3: ★5.0
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"Galactic Dust + Divine Destiny is a meme. You just spend [star] to do damage and get like 200 Block a turn? Absolutely busted combo, love it."
▲ 1400 upvotes
💡 Analysis: An absolute defensive powerhouse that scales infinitely with your [star] expenditure, providing unparalleled survivability in longer encounters. It transforms resource management into a robust defensive engine, encouraging aggressive [star] usage to stack immense Block.
#4
S

Noble Glass Relic

Public effect text for Noble Glass is not available yet. Shared
Versatility: ★4.5 Synergy: ★4.0 Act 1: ★4.5 Act 2: ★4.5 Act 3: ★4.5
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"Noble Glass is my go-to for consistency. Scrying 2 every turn is just *chef's kiss*. Never miss a key card again, feels so good with any character!"
▲ 1150 upvotes
💡 Analysis: This shared relic offers a powerful consistent layer of deck manipulation, allowing players to filter draws and increase the probability of finding critical cards each turn. Its ability to significantly improve hand quality and turn efficiency makes it a strong pickup for any character seeking increased consistency.
#5
S

Fencing Manual Relic

At the start of each combat, Forge 10. Regent Regent
Versatility: ★4.0 Synergy: ★4.0 Act 1: ★4.5 Act 2: ★4.5 Act 3: ★4.0
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"Fencing Manual is wild. If 'Forge' means what I think it means, this relic just lets you pop off from turn 1. Imagine getting 10 of those temporary buffs instantly!"
▲ 1100 upvotes
💡 Analysis: This relic provides a substantial combat-start advantage by instantly providing 10 units of the Regent's unique 'Forge' resource. Its immediate impact can dictate the pace of early turns, offering either powerful offensive boosts or defensive stability, making it incredibly versatile.
#6
S

Divine Right Relic

At the start of each combat, gain [star:3]. Regent Regent
Versatility: ★4.5 Synergy: ★4.5 Act 1: ★4.0 Act 2: ★4.0 Act 3: ★3.5
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"Divine Right is like a mini-Destiny, still super good, especially for ensuring you can play key cards turn 1. Always happy to see it early!"
▲ 850 upvotes
💡 Analysis: A reliable and solid source of turn-one [star], consistently smoothing out initial draws and enabling foundational plays. While overshadowed by Divine Destiny, it remains a strong choice for ensuring early resource availability and maintaining a consistent tempo.
#7
S

Lunar Pastry Relic

At the end of your turn, gain [star:1]. Regent Regent
Versatility: ★4.0 Synergy: ★4.5 Act 1: ★3.0 Act 2: ★4.0 Act 3: ★4.5
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"Lunar Pastry might seem small, but that passive [star] generation adds up like crazy. It's the silent workhorse that lets your bigger combos fire off turn after turn. So underrated!"
▲ 950 upvotes
💡 Analysis: Provides invaluable passive resource generation, guaranteeing a steady supply of [star] for continuous plays and combo extensions throughout combat. Its long-term value significantly enhances resource consistency, making it a subtle but powerful engine for sustained strategies.
#8
A

Vitruvian Minion Relic

Cards containing “Minion” deal double damage and gain double Block. Regent Regent
Versatility: ★2.0 Synergy: ★5.0 Act 1: ★2.5 Act 2: ★4.0 Act 3: ★5.0
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"Vitruvian Minion is the reason I go Minion-builds. Seeing those numbers double just feels so good. It's a true 'build around me' relic and it delivers!"
▲ 1000 upvotes
💡 Analysis: A truly transformative relic for any 'Minion' archetype, multiplying both offensive and defensive outputs of specific cards to game-winning levels. This build-around relic necessitates a dedicated strategy to fully exploit its exponential scaling potential, rewarding commitment with immense power.
#9
A

Regalite Relic

Whenever you create a Colorless card, gain 2 Block. Regent Regent
Versatility: ★2.5 Synergy: ★5.0 Act 1: ★2.0 Act 2: ★3.5 Act 3: ★4.0
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"Regalite feels like it was designed to make those 'colorless spam' builds viable defensively. Get a few generation cards going and suddenly you're an unkillable block machine!"
▲ 700 upvotes
💡 Analysis: This niche relic is a defensive keystone for Colorless card generation archetypes, converting card creation into a reliable source of Block. Its value skyrockets in dedicated builds, offering the crucial survivability needed to execute complex Colorless strategies.
#10
A

Orange Dough Relic

At the start of each combat, add 2 random Colorless cards into your Hand. Regent Regent
Versatility: ★3.0 Synergy: ★3.5 Act 1: ★3.5 Act 2: ★3.0 Act 3: ★2.5
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"Orange Dough is either amazing or completely bricking my hand, lol. When you get a couple of good attacks or blocks, it feels great, but sometimes it's just 'Discard two useless things'."
▲ 600 upvotes
💡 Analysis: Offers immediate card advantage at the start of combat, potentially providing crucial early game plays or synergistic pieces. However, its inherent randomness can sometimes lead to suboptimal draws, making hand management a key consideration when utilizing this relic.

DY

Written by DY (Chief Researcher)

Game QA Professional specializing in technical analysis and meta-data research. Founder of DY Game Lab, dedicated to providing high-fidelity gaming insights, market trends, and competitive tier lists with professional analytical depth.

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