Slay the Spire 2: The Regent Card Tier List — Meta Picks (May 08)

👑 The Regent Card Tier List

Top 15 Meta Picks & Reddit Community Watch (May 08, 2026)

#1
S+

The Sealed Throne Power COST: 1

Ancient Whenever you play a card, gain 1 Star.
Versatility: ★4.5 Synergy: ★5.0 Act 1: ★3.0 Act 2: ★5.0 Act 3: ★5.0
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"Y'all sleeping on The Sealed Throne. Picked this up in Act 1 boss relic and my run became an absolute joke. Infinite Black Hole turns, easy A20 heart kill. It's too good."
▲ 1243 upvotes
💡 Analysis: This ancient artifact fundamentally breaks the Star economy, turning every card played into a resource gain. It's the ultimate enabler for Star-spending archetypes, quickly leading to infinite loops and massive damage potential.
#2
S+

Genesis Power COST: 2

At the start of your turn, gain 1 Star per turn.
Versatility: ★4.0 Synergy: ★4.5 Act 1: ★4.0 Act 2: ★5.0 Act 3: ★5.0
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"Just had a Genesis + Black Hole run that felt like cheating. The consistent Star gain means you're always ready for big plays without worrying about setup. Must-pick if you see it, even in Act 1."
▲ 987 upvotes
💡 Analysis: Genesis offers unparalleled passive Star generation, providing a crucial foundation for any Star-centric Regent build. Its consistent resource drip significantly smooths out turns and enables powerful scaling strategies for the entire run.
#3
S+

Black Hole Power COST: 1

Uncommon Whenever you spend or gain 1 Star, deal 3 damage to ALL enemies.
Versatility: ★4.0 Synergy: ★5.0 Act 1: ★3.5 Act 2: ★5.0 Act 3: ★5.0
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"If you have *any* Star generation, Black Hole is just free damage. With Sealed Throne, it's basically an auto-win button. Feels so good to watch those numbers tick up across the board, trivializing multi-enemy fights."
▲ 1102 upvotes
💡 Analysis: Black Hole is the premier damage scaling card for Star builds, turning every Star generated or spent into significant AOE damage. It's the ultimate payoff for consistent Star generation, capable of effortlessly clearing entire enemy waves.
#4
S+

Furnace Power COST: 1

Uncommon At the start of your turn, Forge 4.
Versatility: ★4.0 Synergy: ★4.5 Act 1: ★4.0 Act 2: ★5.0 Act 3: ★5.0
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"Furnace is just free value. Every turn your main weapon gets stronger. By Act 3, my Sovereign Blade was hitting like a truck and AOEing everything thanks to Seeking Edge. So reliable and easy to build around."
▲ 689 upvotes
💡 Analysis: Furnace is the backbone of any Forge build, providing consistent, passive Forge every turn. This constant scaling makes Sovereign Blade an incredibly potent weapon, ensuring your damage output remains high throughout the entire run.
#5
S

Orbit Power COST: 2

Uncommon Every you spend, gain 1 Energy.
Versatility: ★4.0 Synergy: ★5.0 Act 1: ★3.0 Act 2: ★4.5 Act 3: ★5.0
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"Just had my first Orbit run, and holy crap. Infinite energy for days! Paired with Genesis and a couple of 1-Star cost cards, you just chain spells until everything dies. So much fun and utterly broken."
▲ 876 upvotes
💡 Analysis: Orbit is an incredible energy scaling tool, transforming Star expenditure into valuable Energy, and enabling powerful combo turns. When paired with high Star generation, it easily leads to infinite energy and deck cycling, making it a game-breaker.
#6
S

Monarch's Gaze Power COST: 3

Whenever you attack an enemy, it loses 1 Strength this turn.
Versatility: ★4.0 Synergy: ★4.5 Act 1: ★3.5 Act 2: ★4.5 Act 3: ★5.0
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"Monarch's Gaze is so sneaky good. Picked it up on a whim with a couple of multi-hit attacks and suddenly enemies were hitting for nothing. It's like a permanent Weak application that stacks, absolutely trivializes multi-attackers!"
▲ 756 upvotes
💡 Analysis: Monarch's Gaze provides continuous, passive Strength debuffing on every attack, making it an incredibly powerful defensive scaling tool. Its synergy with multi-hit attacks can effectively cripple enemy damage output over the course of a turn, drastically improving survivability.
#7
S

Heavenly Drill Attack COST: 0

Attack Deal 8 damage X times. Double X if it's 4 or more.
Versatility: ★4.0 Synergy: ★4.5 Act 1: ★3.5 Act 2: ★4.5 Act 3: ★5.0
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"If you ever wondered how to kill bosses with Regent, Heavenly Drill is your answer. Pair it with even a little Strength and watch the numbers absolutely explode. It's a fantastic finisher that makes short work of even the toughest foes."
▲ 701 upvotes
💡 Analysis: Heavenly Drill is a massive damage scaling card, capable of delivering immense burst damage, especially with Strength or Vulnerable. The 'double X' mechanic allows it to quickly become a primary win condition for single-target boss fights, clearing health pools rapidly and efficiently.
#8
S

Seeking Edge Power COST: 1

Forge 7. Sovereign Blade now deals damage to ALL enemies.
Versatility: ★3.5 Synergy: ★5.0 Act 1: ★3.0 Act 2: ★4.5 Act 3: ★5.0
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"Seeking Edge + Furnace = easy mode. No more struggling with those triple elite fights. Your main attack just becomes a clean-up crew. One of the strongest Forge cards, hands down, completely changes how you approach combats."
▲ 915 upvotes
💡 Analysis: Seeking Edge transforms Sovereign Blade from a single-target attack into a potent AOE damage source, dramatically improving combat clear speed. It's a meta-defining card for Forge archetypes, making multi-enemy fights trivial.
#9
S

Big Bang Skill COST: 0

Draw 1 card. Gain 1 Energy. Gain 1 Star. Forge 5. Exhaust.
Versatility: ★4.5 Synergy: ★4.0 Act 1: ★4.5 Act 2: ★4.0 Act 3: ★4.0
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"Big Bang is my favorite common. It just does *everything*. Cycles, gives energy, stars, forge... what more could you want? Never skip if you can help it, absolute value town."
▲ 1012 upvotes
💡 Analysis: Big Bang is a remarkably efficient card, offering a potent cocktail of Energy, Star, card draw, and Forge in a single play. This versatile package makes it an excellent pick in almost any Regent deck, smoothing out turns and accelerating your run progression.
#10
S

Dying Star Attack COST: 1

Attack Ethereal. Deal 9 damage to ALL enemies. ALL enemies lose 9 Strength this turn.
Versatility: ★4.0 Synergy: ★3.5 Act 1: ★4.0 Act 2: ★4.5 Act 3: ★5.0
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"Dying Star is the reason I beat A20 Heart with Regent. That -9 Strength AOE is just insane. Turns deadly turns into manageable ones. A must-have for survivability against almost any boss."
▲ 821 upvotes
💡 Analysis: Dying Star offers unparalleled defensive utility, massively reducing incoming damage from multiple enemies by applying a severe Strength debuff. This card is a run-saver against dangerous multi-attack encounters, providing crucial survivability in later acts.
#11
S

Glow Skill COST: 1

Common Gain 1 Star. Draw 1 card. Next turn, draw 1 card.
Versatility: ★4.5 Synergy: ★3.5 Act 1: ★5.0 Act 2: ★4.0 Act 3: ★3.5
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"Glow is probably the best common. Cycles itself, gives you a Star, sets up next turn. Just pure value for 1 Energy. Always happy to see it, especially in Act 1 to smooth out draws."
▲ 954 upvotes
💡 Analysis: Glow is an exceptionally strong common, providing immediate Star generation and card draw while also setting up future turns. Its efficiency and versatility make it a premium pick in almost any deck, particularly early on for establishing tempo.
#12
S

Prophesize Skill COST: 2

Uncommon Draw 6 cards.
Versatility: ★4.0 Synergy: ★3.5 Act 1: ★3.0 Act 2: ★4.5 Act 3: ★5.0
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"If you need to find cards, Prophesize is it. Just makes your deck run so much smoother. Combine with some energy generation and you can basically play your whole deck every turn for epic combos."
▲ 789 upvotes
💡 Analysis: Prophesize offers a massive burst of card draw, which is invaluable for quickly cycling through your deck to find key combo pieces or necessary damage/block. Its raw card advantage dramatically increases consistency and late-game power, essential for A20 heart attempts.
#13
A

Royal Gamble Skill COST: 0

Uncommon Gain 9 Star. Exhaust.
Versatility: ★3.5 Synergy: ★4.5 Act 1: ★3.0 Act 2: ★4.0 Act 3: ★4.5
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"Royal Gamble is basically a button for 'do something powerful this turn.' Paired it with a fully upgraded Radiate and just wiped the floor with the Act 2 boss. Short, sweet, devastating and an instant problem solver."
▲ 721 upvotes
💡 Analysis: Royal Gamble offers an unparalleled burst of Star, allowing for massive one-turn plays that can turn the tide of any fight. It's a key component for activating powerful Star-consuming effects instantly, providing crucial damage or block when you need it most.
#14
A

Comet Attack COST: 0

Attack Deal 33 damage. Apply 3 Weak. Apply 3 Vulnerable.
Versatility: ★4.0 Synergy: ★3.0 Act 1: ★4.5 Act 2: ★4.0 Act 3: ★3.5
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"Comet is just a fantastic 'delete' button for elites and even some bosses. The Weak and Vulnerable are just icing on the cake. Great card for pushing through tough fights quickly and safely."
▲ 678 upvotes
💡 Analysis: Comet delivers an immense burst of damage coupled with potent Weak and Vulnerable, making it a powerful solution for high-HP enemies or setting up bigger combo turns. Its efficiency for dealing immediate threats is top-tier and helps push through early elites.
#15
A

The Smith Skill COST: 1

Forge 30.
Versatility: ★3.0 Synergy: ★4.0 Act 1: ★3.0 Act 2: ★4.0 Act 3: ★4.5
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"Was having a rough Forge run, picked up The Smith, and suddenly my Sovereign Blade was dealing 50 damage and hitting 3 times. Instantly viable. Great emergency button for scaling, especially if you get it early-mid game."
▲ 589 upvotes
💡 Analysis: The Smith provides an immense burst of Forge, instantly pushing Sovereign Blade into powerhouse territory or activating other Forge-related payoffs. It's a potent way to accelerate your scaling and ensures you have a strong damage baseline for any encounter.

DY

Written by DY (Chief Researcher)

Game QA Professional specializing in technical analysis and meta-data research. Founder of DY Game Lab, dedicated to providing high-fidelity gaming insights, market trends, and competitive tier lists with professional analytical depth.

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