Slay the Spire 2: The Regent Card Tier List — Meta Picks (May 22)
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👑 The Regent Card Tier List
Top 15 Meta Picks & Reddit Community Watch (May 22, 2026)
#1
S+
Black Hole Power COST: 1
Uncommon Whenever you spend or gain 1 Star, deal 3 damage to ALL enemies.
Versatility: ★3.5
Synergy: ★5.0
Act 1: ★4.0
Act 2: ★5.0
Act 3: ★5.0
REDDIT META WATCH
"Black Hole is just *chef's kiss*. Paired with any decent Star generator, it's basically a free win for hallway fights and shreds elites. The numbers just stack up so fast!"
▲ 312 upvotes
💡 Analysis: Black Hole transforms Star generation and expenditure into massive, constant AoE damage, turning your resource engine into an offensive powerhouse. It scales incredibly well throughout the run, making even small Star gains contribute significantly to enemy health bars.
#2
S
The Sealed Throne Power COST: 1
Ancient Whenever you play a card, gain 1 Star.
Versatility: ★3.0
Synergy: ★5.0
Act 1: ★4.0
Act 2: ★5.0
Act 3: ★5.0
REDDIT META WATCH
"Oh man, The Sealed Throne is an absolute game-changer. If you see this Act 1, you just auto-pick it and pivot into a Star build. So much fun chaining those huge Star-spenders!"
▲ 287 upvotes
💡 Analysis: This relic-like card is a core engine for any Star-focused Regent build, turning every card play into a resource gain. Its passive Star generation allows for explosive turns and enables otherwise costly Star-spending abilities to be played freely.
#3
S
Prophesize Skill COST: 2
Uncommon Draw 6 cards.
Versatility: ★5.0
Synergy: ★3.0
Act 1: ★4.0
Act 2: ★5.0
Act 3: ★5.0
REDDIT META WATCH
"Draw 6 cards? Say less. This card is how you find your combos, or just get out of a bad hand. Never skip Prophesize if you need card velocity."
▲ 167 upvotes
💡 Analysis: Prophesize is a foundational card manipulation tool, offering an immense draw of 6 cards for raw deck cycling and combo assembly. Its ability to quickly dig for key pieces makes it a high-priority pick for any deck aiming for consistency or specific card-based interactions.
#4
S
Dying Star Attack COST: 1
Attack Ethereal. Deal 9 damage to ALL enemies. ALL enemies lose 9 Strength this turn.
Versatility: ★4.0
Synergy: ★3.5
Act 1: ★4.5
Act 2: ★5.0
Act 3: ★5.0
REDDIT META WATCH
"If you're struggling with a particular Act 2 elite or boss, Dying Star is an instant solution. -9 Strength for a turn is just bonkers. It's like having multiple Incenses from the Ironclad, but better."
▲ 265 upvotes
💡 Analysis: Dying Star is a game-changing defensive and offensive tool, simultaneously dealing AoE damage and applying a crippling Strength debuff to all enemies. Its Ethereal nature makes it a one-time use, but that single use can completely neutralize an entire turn of enemy attacks, especially against high-Strength elites or multi-attacking bosses.
#5
S
Genesis Power COST: 2
At the start of your turn, gain 1 Star per turn.
Versatility: ★4.0
Synergy: ★4.5
Act 1: ★4.5
Act 2: ★4.5
Act 3: ★4.0
REDDIT META WATCH
"Genesis is so underrated sometimes. Just knowing you're getting that free Star every turn really opens up your deck building and lets you focus on big Star-spenders without worrying about running dry."
▲ 189 upvotes
💡 Analysis: Genesis offers unparalleled consistent Star generation, acting as a reliable baseline for any Regent strategy relying on this resource. Its passive effect allows for strategic planning and ensures you always have a growing pool of Stars for powerful plays.
#6
S
Comet Attack COST: 0
Attack Deal 33 damage. Apply 3 Weak. Apply 3 Vulnerable.
Versatility: ★4.5
Synergy: ★3.0
Act 1: ★5.0
Act 2: ★5.0
Act 3: ★4.0
REDDIT META WATCH
"Comet is the real MVP. Just *poof* and half their health is gone, plus they take more damage and hit for less? Insane value. Definitely one of the best damage cards in the game."
▲ 215 upvotes
💡 Analysis: Comet is a premium damage card, offering a massive burst of unscaled damage alongside potent Weak and Vulnerable debuffs. Its raw power makes it an excellent addition to almost any Regent deck, providing crucial burst for elites and bosses across all acts.
#7
S
Orbit Power COST: 2
Uncommon Every you spend, gain 1 Energy.
Versatility: ★3.5
Synergy: ★5.0
Act 1: ★3.0
Act 2: ★4.5
Act 3: ★5.0
REDDIT META WATCH
"Okay, Orbit + The Sealed Throne + Black Hole is literally the infinite combo. You play a card, get a Star, spend a Star, get Energy, deal damage. Repeat until everything is dead. It's too good."
▲ 456 upvotes
💡 Analysis: Orbit is an incredible energy conduit, transforming Star expenditure into valuable Energy that fuels massive turns. This card is pivotal for any Star-focused deck, allowing you to chain numerous powerful abilities and overcome traditional Energy limitations.
#8
S
Void Form Power COST: 3
Ethereal. End your turn. The first 2 cards you play each turn are free to play.
Versatility: ★4.0
Synergy: ★4.0
Act 1: ★3.5
Act 2: ★4.5
Act 3: ★5.0
REDDIT META WATCH
"Void Form is a high-skill ceiling card but my god is it strong. Paired with some retained cards or big cost spells, you can have absolutely ridiculous turns. Just remember to play it *after* you've done everything else on your current turn, haha."
▲ 231 upvotes
💡 Analysis: Void Form provides incredible energy cheating by making the first two cards free each turn, allowing for massive tempo swings and enabling high-cost strategies. While it ends your current turn, the consistent energy boost it provides over subsequent turns makes it a potent scaling tool.
#9
S
Kingly Kick Attack COST: 1
Attack Uncommon Deal 27 damage. Whenever you draw this card, reduce its cost by 1.
Versatility: ★4.5
Synergy: ★3.0
Act 1: ★4.0
Act 2: ★4.5
Act 3: ★5.0
REDDIT META WATCH
"Kingly Kick is basically a free 'deal 27 damage' button by Act 3 if you draw it enough. It's just consistently good damage that scales perfectly with card draw."
▲ 198 upvotes
💡 Analysis: Kingly Kick is a phenomenal self-scaling damage card, offering substantial initial damage that only gets cheaper and more spammable as you cycle through your deck. Its inherent cost reduction allows it to become a free, high-impact attack in longer combats or well-tuned decks.
#10
S
Meteor Shower Attack COST: 0
Attack Ancient Deal 14 damage to ALL enemies. Apply 2 Weak and Vulnerable to ALL enemies.
Versatility: ★4.5
Synergy: ★3.0
Act 1: ★5.0
Act 2: ★4.5
Act 3: ★4.0
REDDIT META WATCH
"Meteor Shower is one of my favorite Act 1 pickups. It single-handedly carries you through so many hallway fights and even makes elites way easier. Double debuffs and AoE? Yes, please."
▲ 205 upvotes
💡 Analysis: Meteor Shower is an exceptionally strong AoE utility card, providing reliable damage to all enemies coupled with crucial Weak and Vulnerable debuffs. Its early game impact for clearing hallways and softening elites is immense, while the debuffs remain valuable throughout the entire run.
#11
S
Summon Forth Skill COST: 1
Uncommon Retain. Forge 8. Put Sovereign Blade into your Hand from anywhere.
Versatility: ★3.5
Synergy: ★5.0
Act 1: ★3.0
Act 2: ★4.0
Act 3: ★5.0
REDDIT META WATCH
"Summon Forth is a MUST if you're going for a Sovereign Blade build. No more praying for draws, just slap it down, Forge, and get that big sword in hand. The Retain is just icing on the cake."
▲ 210 upvotes
💡 Analysis: Summon Forth is the cornerstone for any Sovereign Blade strategy, guaranteeing immediate access to your primary attack card while also providing a solid chunk of Forge. Its Retain keyword ensures you can hold it for the opportune moment, making your Sovereign Blade plays highly consistent and impactful.
#12
S
Reflect Skill COST: 1
Uncommon Gain 17 Block. Blocked attack damage is reflected to your attacker this turn.
Versatility: ★4.0
Synergy: ★3.0
Act 1: ★4.0
Act 2: ★4.5
Act 3: ★4.5
REDDIT META WATCH
"Reflect is the ultimate 'no u' card. Oh, you're going to hit me for 60? I'll block it and hit you back for 60. So satisfying against certain bosses. Just watch out for statuses!"
▲ 178 upvotes
💡 Analysis: Reflect offers a powerful defensive and offensive package, providing substantial block alongside a unique damage reflection mechanic. This card can single-handedly turn the tide against high-damage enemies or multi-attackers, making it a stellar defensive option.
#13
S
Bulwark Skill COST: 2
Uncommon Gain 13 Block. Forge 10.
Versatility: ★4.0
Synergy: ★4.0
Act 1: ★4.0
Act 2: ★4.0
Act 3: ★4.0
REDDIT META WATCH
"Bulwark is just solid all around. Good block, and that Forge 10 is huge for getting your Sovereign Blade or other Forge stuff online quickly. Always happy to see it."
▲ 155 upvotes
💡 Analysis: Bulwark provides a robust defensive option with a very respectable 13 Block, while simultaneously contributing a significant Forge value. This dual utility makes it a high-priority pick for both early-game survival and long-term Forge-based scaling strategies.
#14
S
Furnace Power COST: 1
Uncommon At the start of your turn, Forge 4.
Versatility: ★3.5
Synergy: ★4.5
Act 1: ★3.5
Act 2: ★4.0
Act 3: ★4.5
REDDIT META WATCH
"Found Furnace in Act 1 once and decided to go all-in on Sovereign Blade. It was amazing, felt like the Blade was just getting stronger every single turn. Highly recommend."
▲ 142 upvotes
💡 Analysis: Furnace offers consistent, passive Forge generation at the start of each turn, forming a reliable engine for any Forge-centric Regent build. Its incremental value allows for steady scaling of Sovereign Blade and other Forge-dependent effects, making it a cornerstone for those archetypes.
#15
A
Seeking Edge Power COST: 1
Forge 7. Sovereign Blade now deals damage to ALL enemies.
Versatility: ★3.0
Synergy: ★5.0
Act 1: ★2.5
Act 2: ★4.0
Act 3: ★5.0
REDDIT META WATCH
"Seeking Edge is how you turn your Sovereign Blade into a hallway clearing machine. It might feel a bit slow to get going, but once that Blade hits all enemies for huge damage, it's just *chef's kiss*. So satisfying."
▲ 195 upvotes
💡 Analysis: Seeking Edge is a transformative card for Sovereign Blade, converting its single-target prowess into potent AoE damage, while also adding a valuable Forge bonus. This card dramatically increases the utility and scaling potential of Sovereign Blade, making it viable for both single-target and multi-enemy combats.
🔍 Latest Analysis
DY
Written by DY (Chief Researcher)
Game QA Professional specializing in technical analysis and meta-data research. Founder of DY Game Lab, dedicated to providing high-fidelity gaming insights, market trends, and competitive tier lists with professional analytical depth.
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