Slay the Spire 2: The Regent Card Tier List — Meta Picks (May 29)

👑 The Regent Card Tier List

Top 15 Meta Picks & Reddit Community Watch (May 29, 2026)

#1
S+

The Sealed Throne Power COST: 1

Ancient Whenever you play a card, gain 1 Star.
Versatility: ★4.5 Synergy: ★5.0 Act 1: ★4.0 Act 2: ★5.0 Act 3: ★5.0
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"OMG, Sealed Throne is just... unfair. Paired with Orbit and Black Hole, it's an auto-win. Literally feels like I'm playing a different character when this drops. #BrokenButFun"
▲ 785 upvotes
💡 Analysis: This Ancient card is arguably the single most impactful Star generation engine in the game, transforming every card play into a valuable resource gain. It immediately defines any run it enters, pushing towards high card-play density and Star-synergy strategies.
#2
S+

Glimmer Skill COST: 1

Uncommon Draw 3 cards. Put 1 card from your Hand on top of your Draw Pile.
Versatility: ★5.0 Synergy: ★4.0 Act 1: ★4.5 Act 2: ★5.0 Act 3: ★5.0
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"Glimmer is so good, it's boring. But it's boring in the same way eating a balanced meal is boring – it keeps you alive and thriving. Draw 3 and filter is just *chef's kiss*."
▲ 380 upvotes
💡 Analysis: Glimmer is a top-tier card manipulation tool, offering significant card draw while also allowing precise deck control by placing a card on top of the draw pile. This consistency is invaluable for finding key pieces and setting up future turns.
#3
S+

Genesis Power COST: 2

At the start of your turn, gain 1 Star per turn.
Versatility: ★4.5 Synergy: ★4.5 Act 1: ★4.0 Act 2: ★5.0 Act 3: ★5.0
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"Genesis is just good, plain and simple. Not flashy, but you never regret picking it. It's the silent workhorse that makes the whole Star engine hum."
▲ 480 upvotes
💡 Analysis: Genesis offers reliable and passive Star generation every turn, forming a solid foundation for any Star-focused build. Its consistency allows for predictable scaling and empowers Star-spending cards throughout the run.
#4
S+

Convergence Skill COST: 1

Uncommon Next turn, gain 1 Energy and 1 Star. Retain your Hand this turn.
Versatility: ★4.5 Synergy: ★4.5 Act 1: ★4.0 Act 2: ★5.0 Act 3: ★5.0
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"Convergence is slept on. Retain Hand is broken in Slay the Spire, and getting extra energy/star on top? Yes, please. This card saves me from bad draws constantly."
▲ 400 upvotes
💡 Analysis: Convergence is a tactical powerhouse, offering critical hand retention that allows for precise planning and setup turns. The bonus Energy and Star further solidify its value, making it a cornerstone for complex strategies and burst damage setups.
#5
S+

Alignment Skill COST: 0

Uncommon Gain 2 Energy.
Versatility: ★5.0 Synergy: ★3.0 Act 1: ★5.0 Act 2: ★5.0 Act 3: ★5.0
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"People always hype up the flashy cards, but Alignment is just pure value. More energy means more plays, simple as that. Never skip this."
▲ 420 upvotes
💡 Analysis: Alignment is a straightforward yet incredibly powerful energy card, providing a critical boost that enables more card plays and opens up complex turns. Its sheer efficiency and universal applicability make it an instant pick.
#6
S+

Orbit Power COST: 2

Uncommon Every you spend, gain 1 Energy.
Versatility: ★4.0 Synergy: ★5.0 Act 1: ★3.5 Act 2: ★5.0 Act 3: ★5.0
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"Orbit is the actual unsung hero. People talk about the big Star generators, but Orbit is what makes them *work*. Free turns, infinite loops, it's just pure Slay the Spire goodness."
▲ 620 upvotes
💡 Analysis: Orbit weaponizes Star generation by converting it directly into Energy, removing the primary constraint on card play. This creates explosive turns, allowing Regent to play an absurd number of cards and unleash devastating combos.
#7
S

Black Hole Power COST: 1

Uncommon Whenever you spend or gain 1 Star, deal 3 damage to ALL enemies.
Versatility: ★4.0 Synergy: ★5.0 Act 1: ★3.0 Act 2: ★4.5 Act 3: ★5.0
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"I just had a run where I gained 50 Star in one turn with Sealed Throne + Orbit, then Black Hole did like 150 AoE damage. My jaw dropped. It's just wild."
▲ 710 upvotes
💡 Analysis: Black Hole provides unparalleled AoE damage scaling, transforming every Star gain or spend into a significant threat. It's the primary payoff for building a Star-centric deck, ensuring consistent damage against all enemies.
#8
S

Void Form Power COST: 3

Ethereal. End your turn. The first 2 cards you play each turn are free to play.
Versatility: ★4.0 Synergy: ★4.5 Act 1: ★3.5 Act 2: ★4.5 Act 3: ★5.0
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"Void Form has saved my runs so many times. Just knowing you have two free plays next turn opens up so many possibilities. It's a true high-risk, high-reward card."
▲ 550 upvotes
💡 Analysis: Void Form is an unparalleled energy cheat, allowing for explosive turns by making the first two cards free. While it requires careful sequencing and a sacrificial turn, the payoff for setting up massive damage or defense is immense.
#9
S

Comet Attack COST: 0

Attack Deal 33 damage. Apply 3 Weak. Apply 3 Vulnerable.
Versatility: ★4.5 Synergy: ★4.0 Act 1: ★4.5 Act 2: ★4.5 Act 3: ★4.0
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"Comet is basically a 'delete' button for any elite you don't like. 33 damage + Weak/Vulnerable? That's just free real estate. My go-to heavy hitter."
▲ 450 upvotes
💡 Analysis: Comet is a powerhouse burst attack, dealing massive damage and applying potent Weak and Vulnerable debuffs simultaneously. It's a fantastic solution for quickly dispatching tough single targets or softening up priority enemies.
#10
S

Monologue Skill COST: 0

Uncommon Whenever you play a card this turn, gain 1 Strength this turn.
Versatility: ★4.0 Synergy: ★4.5 Act 1: ★3.5 Act 2: ★4.5 Act 3: ★5.0
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"Monologue is quietly one of the best scaling cards. Just play cards, get strong. It's so simple but so effective, especially with multi-hit attacks. Love it!"
▲ 390 upvotes
💡 Analysis: Monologue offers exceptional Strength scaling for multi-play decks, transforming every card into a damage multiplier. It significantly enhances the effectiveness of all attacks and can lead to incredible burst turns.
#11
S

Dying Star Attack COST: 1

Attack Ethereal. Deal 9 damage to ALL enemies. ALL enemies lose 9 Strength this turn.
Versatility: ★4.0 Synergy: ★4.0 Act 1: ★4.0 Act 2: ★4.5 Act 3: ★4.5
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"Dying Star is my go-to for elites. The amount of damage it prevents, combined with the damage it deals, is just insane. Ethereal is a small price to pay."
▲ 490 upvotes
💡 Analysis: Dying Star delivers an impactful burst of AoE damage coupled with a substantial Strength debuff to all enemies. This dual utility makes it exceptional for mitigating damage and clearing challenging multi-enemy encounters efficiently.
#12
S

Meteor Shower Attack COST: 0

Attack Ancient Deal 14 damage to ALL enemies. Apply 2 Weak and Vulnerable to ALL enemies.
Versatility: ★4.0 Synergy: ★4.0 Act 1: ★4.0 Act 2: ★4.5 Act 3: ★4.5
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"Ancient rarity usually means 'event card' or super rare, but if I could draft Meteor Shower, I'd take it every time. Weak + Vulnerable ALL enemies is just too good."
▲ 530 upvotes
💡 Analysis: As an Ancient rarity card, Meteor Shower lives up to its name, providing substantial AoE damage alongside critical Weak and Vulnerable debuffs. This dual-purpose effect significantly improves both offense and defense in any multi-enemy encounter.
#13
S

Summon Forth Skill COST: 1

Uncommon Retain. Forge 8. Put Sovereign Blade into your Hand from anywhere.
Versatility: ★3.0 Synergy: ★5.0 Act 1: ★3.5 Act 2: ★4.0 Act 3: ★4.5
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"You *have* to pick Summon Forth if you want to run Sovereign Blade. It's not optional. Retain makes it so flexible, too. Just gotta find the Blade!"
▲ 310 upvotes
💡 Analysis: Summon Forth is the cornerstone of any Sovereign Blade build, guaranteeing access to the powerful weapon while also providing a significant Forge bonus. Its Retain keyword ensures you can hold onto it for the optimal moment.
#14
S

Hammer Time Power COST: 2

Whenever you Forge, all allies Forge as well.
Versatility: ★3.5 Synergy: ★4.5 Act 1: ★3.5 Act 2: ★4.0 Act 3: ★4.5
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"Hammer Time is Forge-meta. Seriously, if you're going for Sovereign Blade, this is a must-have. Twice the Forge for the same card plays? Yes, please."
▲ 300 upvotes
💡 Analysis: Hammer Time dramatically amplifies Forge generation, effectively doubling its output for all Forge-related effects. This card is an absolute must-pick for any build centered around scaling Sovereign Blade or other Forge payoffs.
#15
A

Radiate Attack COST: 0

Attack Uncommon Deal 3 damage to ALL enemies for each 1 Star gained this turn.
Versatility: ★3.5 Synergy: ★4.5 Act 1: ★3.0 Act 2: ★4.0 Act 3: ★4.5
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"Radiate + Genesis is an oldie but a goodie. It's like a mini-Black Hole that hits all enemies based on how much Star you've gained, not just spent. Synergy for days."
▲ 350 upvotes
💡 Analysis: Radiate offers another potent AoE damage outlet for Star-generating decks, rewarding consistent Star gains with significant burst potential. It complements Black Hole perfectly, creating a formidable Star-powered offensive strategy.

DY

Written by DY (Chief Researcher)

Game QA Professional specializing in technical analysis and meta-data research. Founder of DY Game Lab, dedicated to providing high-fidelity gaming insights, market trends, and competitive tier lists with professional analytical depth.

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