Slay the Spire 2: The Regent Relic Tier List — Meta Picks (May 29)

👑 The Regent Relic Tier List

Top 15 Meta Picks & Reddit Community Watch (May 29, 2026)

#1
S+

Divine Destiny Relic

At the start of each combat, gain [star:6]. Regent
Versatility: ★5.0 Synergy: ★4.5 Act 1: ★5.0 Act 2: ★4.5 Act 3: ★4.0
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"Divine Destiny is just *chef's kiss*. Turns my 'can I afford this?' into 'how many times can I play this?' instantly. Act 1 boss on turn 2? Yes, please. #StarPower"
▲ 250 upvotes
💡 Analysis: This relic offers a massive immediate power spike, enabling expensive cards or powerful turn one plays right from the start of combat. It's a foundational piece for any star-economy build, ensuring you hit key thresholds early.
#2
S+

Mini Regent Relic

The first time you spend [star:1] each turn, gain 1 Strength. Regent Regent
Versatility: ★4.5 Synergy: ★5.0 Act 1: ★4.0 Act 2: ★4.5 Act 3: ★5.0
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"Mini Regent is basically free wins if you can reliably spend *any* star. Turn 3 and I'm hitting for +3 Strength every hit? Yes, that's called a steamroll. #OpRelic"
▲ 320 upvotes
💡 Analysis: This relic provides unparalleled offensive scaling, turning any star expenditure into increasing damage output. Its consistent nature means that even small star costs contribute significantly over the course of a combat, making it a cornerstone for aggressive builds.
#3
S

Galactic Dust Relic

For every 10 [star:1] spent, gain 10 Block. Regent Regent
Versatility: ★4.0 Synergy: ★5.0 Act 1: ★3.0 Act 2: ★4.5 Act 3: ★5.0
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"Don't sleep on Galactic Dust! Paired with Lunar Pastry and some cheap star cards, I was getting like 50+ Block a turn by Act 3. Indestructible! #TankGang"
▲ 280 upvotes
💡 Analysis: Galactic Dust is a defensive behemoth for any star-centric deck, converting expended star into substantial Block. It creates a robust scaling engine that can easily outpace enemy damage, making it a key component for late-game survival and long boss fights.
#4
S

Lunar Pastry Relic

At the end of your turn, gain [star:1]. Regent Regent
Versatility: ★4.5 Synergy: ★5.0 Act 1: ★3.5 Act 2: ★4.0 Act 3: ★4.5
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"Lunar Pastry isn't flashy but it's the glue. Without it, my Galactic Dust and Mini Regent felt... hungry. With it? Infinite power baby! #StarEconomy"
▲ 200 upvotes
💡 Analysis: This relic provides a continuous, reliable source of star, forming the backbone of any sustainable star-economy. It ensures that star-hungry relics and cards have the necessary fuel to scale effectively, transforming resource management into a long-term advantage.
#5
A

Vitruvian Minion Relic

Cards containing “Minion” deal double damage and gain double Block. Regent Regent
Versatility: ★2.0 Synergy: ★5.0 Act 1: ★3.0 Act 2: ★4.5 Act 3: ★5.0
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"Okay, Vitruvian Minion is either dead weight or it's absolutely BROKEN. Managed to get a few Minion cards and suddenly my little guys were doing like 40 damage and giving 20 block. Best feeling. #MinionMeta"
▲ 180 upvotes
💡 Analysis: While niche, Vitruvian Minion offers an unparalleled multiplier for a specific archetype, making 'Minion' cards incredibly potent. If the Regent has a dedicated Minion strategy, this relic transforms those cards into combat-ending threats and impenetrable defenses, making it a top-tier build-around.
#6
A

Divine Right Relic

At the start of each combat, gain [star:3]. Regent Regent
Versatility: ★5.0 Synergy: ★4.0 Act 1: ★4.0 Act 2: ★3.5 Act 3: ★3.0
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"Divine Right is like Divine Destiny's chill younger sibling. Not as flashy, but still super solid for getting those early big cards out or just smoothing out my first turn. Always a decent pickup! #Reliable"
▲ 120 upvotes
💡 Analysis: Divine Right provides a solid, immediate boost to star economy at the start of combat, enabling early plays and mitigating resource constraints. While less impactful than its 'Destiny' counterpart, it still offers reliable turn one acceleration for any deck.
#7
A

Fencing Manual Relic

At the start of each combat, Forge 10. Regent Regent
Versatility: ★3.5 Synergy: ★3.5 Act 1: ★3.5 Act 2: ★3.5 Act 3: ★3.5
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"Fencing Manual is clutch for my Forge-focused runs. Still trying to figure out all the best Forge combos but getting 10 upfront feels like a huge headstart every time. #ForgeTheFuture"
▲ 100 upvotes
💡 Analysis: Fencing Manual provides a consistent, unique resource at the start of each combat, hinting at a distinct 'Forge' mechanic for The Regent. Its power is directly tied to the utility and synergy of 'Forge' effects, making it a strong enabler for a potentially powerful character-specific strategy.
#8
A

Regalite Relic

Whenever you create a Colorless card, gain 2 Block. Regent Regent
Versatility: ★2.0 Synergy: ★4.0 Act 1: ★2.0 Act 2: ★2.5 Act 3: ★3.0
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"Regalite is that relic you pick up hoping for that perfect Omniscience/Discovery combo, then it sits there doing nothing. BUT when it works, it works. Had a deck making 3 colorless cards a turn, free block! #NicheButNice"
▲ 70 upvotes
💡 Analysis: Regalite is a highly specialized relic that offers defensive scaling only within a Colorless card generation archetype. Its value is entirely conditional, making it a powerful pick only if your deck consistently creates Colorless cards; otherwise, it provides no benefit.
#9
A

Orange Dough Relic

At the start of each combat, add 2 random Colorless cards into your Hand. Regent Regent
Versatility: ★1.5 Synergy: ★1.0 Act 1: ★2.0 Act 2: ★1.5 Act 3: ★1.0
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"Orange Dough is just chaos in a relic slot. Got an Omniscience one run, a Purity another. Mostly just clogs my hand with garbage when I need consistency. Hard pass unless I'm memeing. #RNGesus"
▲ 40 upvotes
💡 Analysis: Orange Dough introduces significant randomness to your opening hand, making it a high-risk, low-reward relic. While it can occasionally provide a powerful Colorless card, the inconsistency and potential for hand-clogging often outweigh its benefits, especially in crucial late-game combats.

DY

Written by DY (Chief Researcher)

Game QA Professional specializing in technical analysis and meta-data research. Founder of DY Game Lab, dedicated to providing high-fidelity gaming insights, market trends, and competitive tier lists with professional analytical depth.

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